Investigational device · Not cleared by TFDA or FDA · Not available for sale
VARUNA
THE WORLD'S FIRST WEARABLE TREATMENT FOR PALMAR HYPERHIDROSIS

Dry hands, before the sweat starts.

Varuna is the world's first non-invasive wearable for palmar hyperhidrosis. Worn like a watch, it gently stimulates the nerves at your wrist and stops the sweating signal before it reaches your palm. No surgery, no injections, no drugs, and you can take it off anytime.

See how it works For clinicians and partners
The Varuna wristband: a white band with a square face
1st of 40
MEC competition, teams from across Asia
Also: Conrad Innovator Award, Conrad Challenge
Patent pending
Provisional patent filed
Taiwan and US filings in preparation
MOEA-backed
Supported by Taiwan's Ministry of Economic Affairs
Materials, clinical and factory connections
THE PROBLEM

Sweating far beyond what the body needs, and no treatment that fits.

Palmar hyperhidrosis gets in the way of writing, using a phone, shaking hands, and many kinds of work. The options people have today each come with a real cost.

01

Antiperspirants

Often not strong enough for severe cases.

02

Iontophoresis

Needs sessions repeated again and again.

03

Botulinum injections

Painful in the palm, and must be repeated.

04

Sympathectomy

Irreversible surgery that can cause sweating elsewhere.

VARUNA

A world first

The first non-invasive wearable for hyperhidrosis. Removable, and acts before sweating begins.

HOW IT WORKS

The first device to reach the nerve before the sweat reaches the skin.

Varuna sits over the median and ulnar nerves, the two nerves that carry the sweating signal to the palm.

1

Sense

Skin-conductance (GSR) and temperature sensors at the wrist track early signs that sweating is coming.

2

Predict

A model calibrated to each wearer decides when an episode is about to begin.

3

Stimulate

Two electrodes over the nerves deliver gentle stimulation before sweat appears.

visible sweat stimulate predicted onset with Varuna without time → skin conductance
Illustrative only, not measured data.
The Varuna V4 prototype worn on an outstretched wrist
Varuna V4 prototype, in the team's own four-piece casing.
THE DEVICE

Worn like a watch. Off whenever you want.

Varuna is the world's first wrist-worn device to treat hyperhidrosis through wrist nerve stimulation, and the first treatment of any kind designed to act before sweating begins, not after.

Targets
Median and ulnar nerves
Sensing
Galvanic skin response and temperature
Electronics
ESP32 microcontroller, Bluetooth Low Energy
Enclosure
Four-piece wrist casing, designed in-house
EARLY RESULTS

~85%

less palm sweat in a volunteer with severe palmar hyperhidrosis.

A single-participant, preliminary result. Our pre-clinical device trials are now testing it under clinical supervision.

A volunteer sits wearing an electrical stimulator on each wrist
The volunteer wears stimulators on both wrists.
The testing room during a preliminary stimulation session
On site during preliminary testing.
CLINICAL PATH

Where we are, and what comes next.

  1. DONE
    Preliminary test
    First stimulation test on a volunteer with severe symptoms.
  2. IN PROGRESS
    Pre-clinical device trials
    At Wanfang Hospital's electrotherapy department, setting stimulation parameters and measures.
  3. NEXT
    Clinical trials
    Testing Varuna with more patients under clinical supervision.
  4. NEXT
    FDA clearance
    Regulatory clearance to bring Varuna to patients.
Two people high-five; one wears the Varuna wristband
WHY WE BUILT THIS

It started with a friend.

Our best friend has had sweaty palms for as long as we've known him. His test answers smudge before he finishes writing them, and he wipes his hand on his jeans before every handshake. Antiperspirants didn't work, injections were expensive and had to be repeated, and surgery was too big a risk.

We kept asking why there wasn't something he could just wear. So we started building it. Varuna began as a fix for one friend. Now we're building it for everyone who has ever hesitated before a handshake.

Stanley Chiu
Stanley Chiu
Co-founder · CEO
Sebastian Lee
Sebastian Lee
Co-founder · [Role]
Sandy Gou
Co-founder · [Role]

Advisors

Prof. Li
Distinguished Professor, TMU Graduate Institute of Biomedical Informatics; Dermatology attending, Wanfang Hospital
Prof. Chen
Biomedical Engineering, National Cheng Kung University; Co-director, STB × NCKU BioDesign
Prof. Lee
Attending Neurosurgeon, NCKU Hospital; Clinical Professor of Surgery, NCKU
Prof. Lin
Professor and Attending Neurologist, NCKU Hospital
Dr. Tsai
Dermatologist; former Director, Dermatology Laser Center, Wanfang Hospital
The Varuna team seated in a meeting with Dr. Tsai
Early feedback session with Dr. Tsai

Clinicians, researchers, partners: let's talk.

We're looking for clinical collaborators, people living with hyperhidrosis who'd like to follow the project, and partners to help bring Varuna to patients.

[hello@varuna.tw]